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br ing a game changerin advancing cancer
2020-08-30
¨ ing a game¨ changerin advancing cancer diagnosis. This is the case, for instance, for nanoparticle (NP)-based imaging that will likely provide superior diagnostic and prognostic information that is otherwise difficult to obtain, potentially advancing personalized clinical care. Diagnostic vs
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br Introduction br Cervical cancer CeCa represents a
2020-08-30
1. Introduction Cervical cancer (CeCa) represents a major public health problem worldwide, as more than 500,000 new cases and more than 250,000 deaths are detected each year, of which over 80% occur in developing countries [1]. Infection with high-risk human papillomavirus (HR-HPV) is considere
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br Linkage to EMT in cellular morphologies br The
2020-08-30
3.4. Linkage to EMT in cellular morphologies The cellular morphological parameters are chosen to clarify the relationship between the morphology induced by physical prop-erties of substrates and gene expression of typical EMT markers (Figs. 6, 7, and 8). Relative TGFB (Fig. 6), HIF1A (Fig. 7
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br FSH induced PSA expression in androgen
2020-08-30
3.2. FSH-induced PSA expression in androgen independent cells FSH treatment significantly increased the protein level of PSA and AR in C4-2 7558-80-7 (P < 0.03) at the concentration of 50 IU/l (Fig. 2A). The effect of FSH on PSA induction was less pronounced in LNCaP cells with a nonsignificant
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br of g mL of
2020-08-30
of 30 μg/mL of CDDP and 48 h of treatment, (this CDDP concentration corresponds to its IC50 for 48 h exposure). Results reveal that the cell viability was reduced up to 50%, the same as by using free CDDP. Furthermore, when CCN1 and CCN2 nanogels were put in contact with the 33069-62-4 in a co
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br MTT cell viability assay br The cells
2020-08-28
2.5. MTT cell viability assay The cells were incubated for 24, 48 and 72 h with the different NPs/ substances. The cell medium was then aspirated and exchanged with 100 μl of medium containing a final concentration of 250 μg MTT/ml. The incubation was continued for 3 h at 37 °C for formation of
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br In our study four features were identified as
2020-08-24
In our study, four features were identified as most significant predictors of the subtypes: roundness, concavity, gray mean, and correlation. Roundness depicts a lesion's shape, whereas concavity reflects the irregularity of a lesion boundary. Gray mean simply represents the brightness of a lesion
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br There are some study
2020-08-18
There are some study limitations, due to the secondary analysis of an original trial in patients who were selected for the presence of BTcP. Thus, we do not have information about the prevalence of this phe-nomenon in patients with H&N cancer. Moreover, no specific treatment was given, as treatmen
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b http www glpbio com simage GC Erteberel
2020-08-18
r> 3.4. Cortical bone distribution r> There were no differences between groups for average endocortical, midcortical or pericortical vBMD of either the proximal tibia or radius (Table 3). There were also no differences between PCa and healthy controls for any cortical bone distribution outcomes.
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the higher concordance for newer biomarkers such as
2020-08-18
the higher concordance for newer biomarkers such as NRAS. Third, the patients varied in the systemic treatments they received, and the impact of this on the metastasis (tumour regression after chemo- or radiother-apy) may have affected the sequencing result through adequacy of the sample. Fourth, it
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br Aur downregulates the protein level
2020-08-18
3.5. Aur downregulates the protein level of androgen receptor Our previous studies have demonstrated that USP14 could regulate the stability of androgen receptor proteins in PCa and breast carci-nomas (Liao et al., 2017, 2018). Inhibition of USP14 significantly in-creased the degradation of
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br Fig Immunohistochemical IHC analysis of hCG
2020-08-14
Fig. 2. Immunohistochemical (IHC) analysis of hCG and LHCGR expression in tissue microarrays (TMA) collected from patients with epithelial ovarian cancer (EOC). (A–C) IHC staining for hCG expression produced (A) no, (B) weak, and (C) strong staining in normal, benign, and malignant ovarian tissues
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br ACCEPTED MANUSCRIPT br of ROS
2020-08-12
ACCEPTED MANUSCRIPT of ROS on the mitochondrial apoptosis pathway is mediated through the opening of osmotic transition pores, which activate the pore-destabilizing B-cell lymphoma 2 (Bcl-2)-associated X (Bax) protein and inhibit the pore-stabilizing Bcl-2 protein from the Bcl-2 family. The int
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b iframe width height src https www youtube com embed
2020-08-12
r> antibody elicits a significant increase in the M1 tumoricidal subset of macrophages in the TME (P < 0.05) while simultaneously trending toward a reduction in the M2 macrophage subset (P = 0.05) (Fig. 11B), thus contributing to overall antitumor actions of dual antiestrogen-ICI therapy. 4. Dis
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br universe br Display the measured value of greatness
2020-08-12
universe. 2 Display the measured value of greatness (X value) in its unit of measurement. 3 Determine the favorable evidence degree μ by applying a selected mathematical function considering the conditions: 1IfXvalue > Maxvalue μ = selected mathematical function IfXvalue ∈ [Min value ,