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br In order to prove the
2020-08-12
In order to prove the superior performance of the MWCNT on the electrode surface, the CV of thionine immobilized on the GCE/MWCNT/His-rGO was compared with that on the GCE/His-rGO. As seen, the MWCNT/His-rGO/thionine biointerface possesses a larger CV current than the His-rGO/thionine biointerface
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br HP infection HPI and gastric mucosal
2020-08-09
3.3. HP infection (HPI) and gastric mucosal dysbiosis To investigate whether HP colonisation influences the overall struc-ture and composition of the gastric microbiota in specific microhabitats, we examined changes in the gastric microbiota in patients with histo-pathological HP+ and H. pyl
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Balschun K Haag J Wenke A K von Sch nfels
2020-08-09
[102] Balschun K, Haag J, Wenke A-K, von Schönfels W, Schwarz NT, Röcken C. KRAS, NRAS, PIK3CA Exon 20, and BRAF genotypes in synchronous and metachronous primary colorectal cancers: diagnostic and therapeutic implications. J Mol Diagn 2011 Jul 22;13(4):436–45. [103] Sutton PA, Jithesh PV, Jones
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The present results highlight the marked impair ment of
2020-08-07
The present results highlight the marked impair-ment of mitochondrial function in the muscle of cachectic TB mice. Whether reduced mitochondrial respiration is a cause or a consequence of muscle protein hypercatabolism is still unclear. Both condi-tions potentially occur: modulation of mitochondrial
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br Autophagy removes oncogenic proteins and maintains genomi
2020-08-07
3.1.1. Autophagy removes oncogenic proteins and maintains genomic stability p53 is activated in response to a variety of stress conditions, in-cluding DNA damage, oxidative stress, replicative stress, genomic in-stability etc. (Meek, 2015). In cancer cells, the proteasomal degradation of the mu
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br As stage was such a strong predictor of
2020-08-06
As stage was such a strong predictor of survival for women with non-endometrioid cancers (Stage 3, HR 7.1; 95% CI 4.9), the models were further stratified by this factor. In women with non-endometrioid histology and extra-uterine disease at presentation (Stage 3 and 4), age was no longer significa
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br positive surgical margins vs
2020-08-06
.01), positive surgical margins (35.3% vs. 22.1%; P a GSK126 of AA men who underwent RP, we observed an independent as-sociation of low SES with advanced stage or aggressive prostate cancer. By including only patients in a single racial demographic group, we eliminated the potential confounding e
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br We next evaluated whether
2020-08-06
We next evaluated whether there was a joint effect be-tween CTC and ccfDNA level on patient outcomes. To this end, we separated all patients into four risk groups based on their baseline CTC and ccfDNA levels, including: (1) 64 patients with (4) 23 patients with 5 CTCs and high ccfDNA (high risk
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Wood JD Neuropathophysiology of functional gastrointestinal
2020-08-05
[31] Wood JD. Neuropathophysiology of functional gastrointestinal disorders. World J Gastroenterol 2007;13(9):1313–32. [32] Gonlachanvit S, Chey WD, Goodman KJ, Parkman HP. Effect of meal size and test duration on gastric emptying and gastric myoelectrical activity as determined with simultaneous [
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br DISCUSSION br The goal of
2020-08-04
DISCUSSION The goal of this study was to uncover how ARv7 contributes to CRPC development. In this article we show that ARv7 primarily Figure 6. ARv7 Represses Genes with a Tumor-Suppressive Function (A) GSEA of ARfl- and ARv7-specific gene signatures (Table S5), compared with genes ranke
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br The complex and multifaceted process that
2020-08-02
The complex and multifaceted process that defines EMT has attracted much attention in cancer studies and is considered an essen-tial step in the formation of metastases. For these reasons, the search for new drugs capable of inhibiting this process is an essential field of biomedical research. In
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br Fig MPT G treatment
2020-07-31
Fig. 4. MPT0G211 treatment markedly inhibited SSH1 expression and cofilin phosphorylation in MDA-MB-231 cells. Fig. 5. Actin distribution in MDA-MB-231 cells in response to MPT0G211 treatment. (A) MDA-MB-231 cells were treated with MPT0G211 or tubastatin A (10 μM) for 24 h, after which whole
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br Cite this article as LV Yi
2020-07-29
Cite this article as: LV Yi, SO Kwok-Fai, WONG Nai-Kei, XIAO Jia. Anti-cancer activities of S-allylmercaptocysteine from Contents lists available at ScienceDirect Bioorganic & Medicinal Chemistry journal homepage: www.elsevier.com/locate/bmc Anti-cancer activity of m-carborane-containi
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br Only one previous study has reported
2020-07-06
Only one previous study has reported on associations between the non-metallic air toxics and breast cancer risk on a US-wide scale (Hart et al., 2018). In the Nurses' Health Study II (NHSII), 1,2-dibromo-3-chloropropane was the only air toxic that demonstrated a consistent increased risk of bre
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Meyers CA Albitar M Estey E Cognitive impairment fatigue
2020-07-04
[16] Meyers CA, Albitar M, Estey E. Cognitive impairment, fatigue, and cytokine levels in patients with acute myelogenous leukemia or myelodysplastic syndrome. Cancer 2005;104(4):788–93. [17] El-Gohary GM, Azzam HM, Ahmed OI, El-Shokry MH. Pro-inflammatory cytokines and depression in patients with